Rational Alteration of Pharmacokinetics of Chiral Fluorinated and Deuterated Derivatives of Emixustat for Retinal Therapy-Reference-Cited by-同舟云学术

Rational Alteration of Pharmacokinetics of Chiral Fluorinated and Deuterated Derivatives of Emixustat for Retinal Therapy

Published:2021-06-03 Issue:12 Volume:64 Page:8287-8302
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Blum Eliav¹^ORCID,Zhang Jianye²^ORCID,Zaluski Jordan³^ORCID,Einstein David E.⁴⁵^ORCID,Korshin Edward E.¹,Kubas Adam⁶^ORCID,Gruzman Arie¹^ORCID,Tochtrop Gregory P.³,Kiser Philip D.²⁴⁵^ORCID,Palczewski Krzysztof²⁴⁷^ORCID

Affiliation:

1. Department of Chemistry, Faculty of Exact Sciences, Bar-Ilan University, Ramat-Gan 5290002, Israel

2. Department of Ophthalmology, Gavin Herbert Eye Institute, University of California, Irvine, California 92697, United States

3. Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, United States

4. Department of Physiology and Biophysics, University of California, Irvine, California 92697, United States

5. Research Service, VA Long Beach Healthcare System, Long Beach, California 90822, United States

6. Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, Warsaw 01-224, Poland

7. Department of Chemistry, University of California, Irvine, California 92697, United States

Funder

Division of Chemistry

National Eye Institute

Research to Prevent Blindness

U.S. Department of Veterans Affairs

University of California, Irvine

U.S. Department of Defense

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00279

Reference66 articles.

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