Investigation of Janus Kinase (JAK) Inhibitors for Lung Delivery and the Importance of Aldehyde Oxidase Metabolism-Reference-Cited by-同舟云学术

Investigation of Janus Kinase (JAK) Inhibitors for Lung Delivery and the Importance of Aldehyde Oxidase Metabolism

Published:2021-12-20 Issue:1 Volume:65 Page:633-664
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wellaway Christopher R.¹^ORCID,Baldwin Ian R.¹,Bamborough Paul¹^ORCID,Barker Daniel¹,Bartholomew Michelle A.¹,Chung Chun-wa¹^ORCID,Dümpelfeld Birgit²,Evans John P.¹,Fazakerley Neal J.¹,Homes Paul¹,Keeling Steven P.¹,Lewell Xiao Q.¹,McNab Finlay W.¹,Morley Joanne¹,Needham Deborah¹,Neu Margarete¹,van Oosterhout Antoon J. M.¹,Pal Anshu¹,Reinhard Friedrich B. M.²,Rianjongdee Francesco¹^ORCID,Robertson Craig M.¹,Rowland Paul¹,Shah Rishi R.¹^ORCID,Sherriff Emma B.¹,Sloan Lisa A.¹,Teague Simon¹,Thomas Daniel A.¹,Wellaway Natalie¹,Wojno-Picon Justyna¹,Woolven James M.¹,Coe Diane M.¹

Affiliation:

1. GSK, Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K.

2. Cellzome GmbH, A GlaxoSmithKline Company, Meyerhofstraße 1, 69117 Heidelberg, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01765

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