Structure-Based Design of a Chemical Probe Set for the 5-HT5A Serotonin Receptor

Author:

Levit Kaplan Anat1,Strachan Ryan T.2,Braz Joao M.3,Craik Veronica3,Slocum Samuel4,Mangano Thomas4,Amabo Vanessa4,O’Donnell Henry1,Lak Parnian1,Basbaum Allan I.3,Roth Bryan L.245ORCID,Shoichet Brian K.1ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California 94143, United States

2. Department of Pharmacology, School of Medicine, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina 27514, United States

3. Department of Anatomy, University of California, San Francisco, San Francisco, California 94143, United States

4. National Institute of Mental Health Psychoactive Drug Screening Program, School of Medicine, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina 27514, United States

5. Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina 27514, United States

Funder

National Institute of Neurological Disorders and Stroke

Defense Advanced Research Projects Agency

National Institute of Diabetes and Digestive and Kidney Diseases

National Institute of Mental Health

National Institute of General Medical Sciences

Open Philanthropy Project

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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