Discovery of HDAC6-Selective Inhibitor NN-390 with <i>in Vitro</i> Efficacy in Group 3 Medulloblastoma-Reference-Cited by-同舟云学术

Discovery of HDAC6-Selective Inhibitor NN-390 with in Vitro Efficacy in Group 3 Medulloblastoma

Published:2022-02-04 Issue:4 Volume:65 Page:3193-3217
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Nawar Nabanita¹²,Bukhari Shazreh¹²,Adile Ashley A.³,Suk Yujin³,Manaswiyoungkul Pimyupa¹²,Toutah Krimo¹,Olaoye Olasunkanmi O.¹²,Raouf Yasir S.¹²,Sedighi Abootaleb¹^ORCID,Garcha Harsimran Kaur¹²,Hassan Muhammad Murtaza¹²,Gwynne William³,Israelian Johan¹²,Radu Tudor B.¹²,Geletu Mulu¹,Abdeldayem Ayah¹²,Gawel Justyna M.¹,Cabral Aaron D.¹²,Venugopal Chitra³⁴,de Araujo Elvin D.¹,Singh Sheila K.³⁴,Gunning Patrick T.¹²^ORCID

Affiliation:

1. Department of Chemical and Physical Sciences, University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, Ontario L5L 1C6, Canada

2. Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada

3. Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada

4. Department of Surgery, Faculty of Health Sciences, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada

Funder

Canadian Institutes of Health Research

Canada Foundation for Innovation

Canada Research Chairs

Natural Sciences and Engineering Research Council of Canada

Leukemia and Lymphoma Society of Canada

Canadian Breast Cancer Foundation