IMHB-Mediated Chameleonicity in Drug Design: A Focus on Structurally Related PROTACs
Author:
Affiliation:
1. Molecular Biotechnology and Health Sciences Department, CASSMedChem, University of Torino, Via Nizza 44 Bis, Torino 10126, Italy
Publisher
American Chemical Society (ACS)
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c01200
Reference42 articles.
1. New Chemical Modalities and Strategic Thinking in Early Drug Discovery
2. Advancing New Chemical Modalities into Clinical Studies
3. PROteolysis TArgeting Chimeras (PROTACs) — Past, present and future
4. Protacs: Chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation
5. PROTAC targeted protein degraders: the past is prologue
Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Computational methods and key considerations for in silico design of proteolysis targeting chimera (PROTACs);International Journal of Biological Macromolecules;2024-10
2. Molecular properties, including chameleonicity, as essential tools for designing the next generation of oral beyond rule of five drugs;ADMET and DMPK;2024-08-27
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