Natural Product-Inspired Discovery of Naphthoquinone-Furo-Piperidine Derivatives as Novel STAT3 Inhibitors for the Treatment of Triple-Negative Breast Cancer-Reference-Cited by-同舟云学术

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Natural Product-Inspired Discovery of Naphthoquinone-Furo-Piperidine Derivatives as Novel STAT3 Inhibitors for the Treatment of Triple-Negative Breast Cancer

Published:2024-09-03 Issue:17 Volume:67 Page:15291-15310
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Fan Chengcheng¹,Lou Shengying¹,Shen Chenjun²,Liao Jialing¹,Ni Hao¹,Chen Siyu¹,Zhu Zhihui²,Hu Xueping³,Xie Wei¹,Zhao Huajun²,Cui Sunliang¹^ORCID

Affiliation:

1. College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China

2. College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 311402, China

3. Institute of Frontier Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Qingdao 266237, China

Funder

Zhejiang University

National Program for Support of Top-notch Young Professionals

Key Research and Development Program of Zhejiang Province

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Huahai Pharmaceutical Co, LtD.

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c00872

Reference41 articles.

1. Cancer burden in low-income and middle-income countries

2. Breast cancer

3. Treatment landscape of triple-negative breast cancer — expanded options, evolving needs

4. Pathogenesis of Triple-Negative Breast Cancer

5. Pembrolizumab plus Chemotherapy in Advanced Triple-Negative Breast Cancer

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