N-Adamantyl-1-alkyl-4-oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as Fluorescent Probes to Detect Microglia Activation through the Imaging of Cannabinoid Receptor Subtype 2 (CB2R)

Author:

Intranuovo Francesca1,Majellaro Maria23,Mastropasqua Francesco1,Delre Pietro4ORCID,Abatematteo Francesca Serena1,Mangiatordi Giuseppe Felice4ORCID,Stefanachi Angela1ORCID,Brea Josè56ORCID,Loza Maria Isabel56ORCID,Riganti Chiara7ORCID,Ligresti Alessia8ORCID,Kumar Poulami8,Esposito Daniela8,Cristino Luigia8,Nicois Alessandro8ORCID,González Lucía23,Perrone Maria Grazia1,Colabufo Nicola Antonio1ORCID,Sotelo Eddy23ORCID,Abate Carmen1ORCID,Contino Marialessandra1ORCID

Affiliation:

1. Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari ALDO MORO, via Orabona 4, 70125 Bari, Italy

2. Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Universidade de Santiago de Compostela, 15782 Santiago, Spain

3. Departamento de Quimica Orgánica, Facultade de Farmacia, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain

4. Institute of Crystallography, National Research Council of Italy, Via Amendola, 122/o, 70126 Bari, Italy

5. Innopharma Screening Platform, BioFarma Research Group, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), University of Santiago de Compostela, 15782 Santiago de Compostela, Spain

6. Department of Pharmacology, Pharmacy and Pharmaceutical Technology. School of Pharmacy, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain

7. Dipartimento di Oncologia, Università degli Studi di Torino, 10124 Torino, Italy

8. National Research Council of Italy, Institute of Biomolecular Chemistry, 80078 Pozzuoli (NA), Italy

Publisher

American Chemical Society (ACS)

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