Discovery, Crystallographic Studies, and Mechanistic Investigations of Novel Phenylalanine Derivatives Bearing a Quinazolin-4-one Scaffold as Potent HIV Capsid Modulators-Reference-Cited by-同舟云学术

Discovery, Crystallographic Studies, and Mechanistic Investigations of Novel Phenylalanine Derivatives Bearing a Quinazolin-4-one Scaffold as Potent HIV Capsid Modulators

Published:2023-12-06 Issue:23 Volume:66 Page:16303-16329
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Xu Shujing¹,Sun Lin¹^ORCID,Barnett Michael²,Zhang Xujie¹^ORCID,Ding Dang¹,Gattu Anushka³,Shi Dazhou¹,Taka Jamie R. H.²,Shen Wenli¹,Jiang Xiangyi¹,Cocklin Simon⁴^ORCID,De Clercq Erik⁵^ORCID,Pannecouque Christophe⁵,Goldstone David C.²^ORCID,Liu Xinyong¹^ORCID,Dick Alexej³,Zhan Peng¹^ORCID

Affiliation:

1. Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, 44 West Culture Road, 250012 Jinan, Shandong, PR China

2. School of Biological Sciences, The University of Auckland, 3A Symonds St, Auckland 1010, New Zealand

3. Department of Biochemistry & Molecular Biology, Drexel University College of Medicine, Philadelphia, Pennsylvania 19102, United States

4. Specifica Inc., The Santa Fe Railyard, 1607 Alcaldesa Street, Santa Fe, New Mexico 87501, United States

5. Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, K.U. Leuven, Herestraat 49 Postbus 1043 (09.A097), B-3000 Leuven, Belgium

Funder

National Institute of Allergy and Infectious Diseases

Taishan Scholar Project of Shandong Province

Shandong University

Natural Science Foundation of Shandong Province

National Natural Science Foundation of China

Science Foundation for Outstanding Young Scholars of Shandong Province

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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