C-2 Thiophenyl Tryptophan Trimers Inhibit Cellular Entry of SARS-CoV-2 through Interaction with the Viral Spike (S) Protein-Reference-Cited by-同舟云学术

C-2 Thiophenyl Tryptophan Trimers Inhibit Cellular Entry of SARS-CoV-2 through Interaction with the Viral Spike (S) Protein

Published:2023-07-20 Issue:15 Volume:66 Page:10432-10457
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gargantilla Marta¹,Francés Clara²^ORCID,Adhav Anmol³^ORCID,Forcada-Nadal Alicia³⁴^ORCID,Martínez-Gualda Belén¹,Martí-Marí Olaia¹,López-Redondo María Luisa³,Melero Roberto⁵,Marco-Marín Clara³⁴,Gougeard Nadine³⁴^ORCID,Espinosa Carolina³^ORCID,Rubio-del-Campo Antonio³^ORCID,Ruiz-Partida Rafael³,Hernández-Sierra María del Pilar³^ORCID,Villamayor-Belinchón Laura³,Bravo Jerónimo³^ORCID,Llacer José-Luis³⁴^ORCID,Marina Alberto³⁴^ORCID,Rubio Vicente³⁴,San-Félix Ana¹^ORCID,Geller Ron²,Pérez-Pérez María-Jesús¹^ORCID

Affiliation:

1. Instituto de Química Médica (IQM, CSIC), c/Juan de la Cierva 3, Madrid 28006, Spain

2. Institute for Integrative Systems Biology (I2SysBio), UV-CSIC, c/Catedrático Agustin Escardino, 9, Paterna 46980, Valencia, Spain

3. Instituto de Biomedicina de Valencia (IBV, CSIC), c/Jaime Roig 11, Valencia 46010, Spain

4. Group 739, Centro de Investigación Biomédica en Red en Enfermedades Raras (CIBERER-ISCIII), Madrid 28049, Spain

5. Centro Nacional de Biotecnología (CNB, CSIC), c/Darwin 3, Madrid 28049, Spain

Funder

European Commission

Fondo Supera Covid-19

Instituto de Salud Carlos III

Generalitat Valenciana y Conselleria de Innovaci??n, Universidades, Ciencia y Sociedad

Agencia Estatal Consejo Superior de Investigaciones Cientificas

Agencia Estatal de Investigaci??n,Ministerio de Ciencia, Innovaci??n y Universidades

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c00576

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