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Combinatorial Ubiquitination REal-time PROteolysis (CURE-PROs): A Modular Platform for Generating Reversible, Self-Assembling Bifunctional Targeted Degraders

  • Published:2024-03-30 Issue:7 Volume:67 Page:5473-5501
  • ISSN:0022-2623
  • Container-title:Journal of Medicinal Chemistry
  • language:en
  • Short-container-title:J. Med. Chem.

Author:

Giardina Sarah F.1ORCID,Valdambrini Elena1,Singh Pradeep K.2,Bacolod Manny D.1,Babu-Karunakaran Ganesh3,Peel Michael4,Warren J. David2ORCID,Barany Francis1ORCID

Affiliation:

1. Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York 10065, United States

2. Department of Biochemistry, Weill Cornell Medicine, New York, New York 10065, United States

3. Syngene International Limited, Bangalore 560 099, India

4. MRP Pharma LLC, Chapel Hill, North Carolina 27514, United States

Funder

Weill Cornell Medicine

Unii Therapeutics

TwiXimo Therapeutics

Publisher

American Chemical Society (ACS)

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