Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma

Author:

Mizuguchi Mineyuki1ORCID,Nakagawa Yusuke2,Yokoyama Takeshi1ORCID,Okada Takuya23ORCID,Fujii Kanako4,Takahashi Kanoko5,Luan Nguyen Ngoc Thanh2,Nabeshima Yuko1,Kanamitsu Kayoko6,Nakagawa Shinsaku7,Yamakawa Shiori8,Ueda Mitsuharu8,Ando Yukio9,Toyooka Naoki23ORCID

Affiliation:

1. Faculty of Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Japan

2. Graduate School of Innovative Life Science, University of Toyama, Toyama 930-8555, Japan

3. Faculty of Engineering, University of Toyama, Toyama 930-8555, Japan

4. Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Japan

5. Graduate School of Pharma-Medical Sciences, University of Toyama, Toyama 930-8555, Japan

6. Graduate School of Pharmaceutical Sciences, the University of Tokyo, Tokyo 113-0033, Japan

7. Graduate School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan

8. Department of Neurology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860-8556, Japan

9. Faculty of Pharmaceutical Sciences, Nagasaki International University, Sasebo 859-3298, Japan

Funder

Tamura Science and Technology Foundation

Japan Agency for Medical Research and Development

Japan Science and Technology Agency

Publisher

American Chemical Society (ACS)

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