Synthetic Approaches to Novel Human Carbonic Anhydrase Isoform Inhibitors Based on Pyrrol-2-one Moiety-Reference-Cited by-同舟云学术

Synthetic Approaches to Novel Human Carbonic Anhydrase Isoform Inhibitors Based on Pyrrol-2-one Moiety

Published:2024-02-01 Issue:4 Volume:67 Page:3018-3038
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Al-Matarneh Cristina M.¹²^ORCID,Pinteala Mariana¹,Nicolescu Alina³,Silion Mihaela⁴,Mocci Francesca⁵^ORCID,Puf Razvan¹,Angeli Andrea⁶^ORCID,Ferraroni Marta⁷^ORCID,Supuran Claudiu T.⁶^ORCID,Zara Susi⁸,Carradori Simone⁸^ORCID,Paoletti Niccolò⁵⁶^ORCID,Bonardi Alessandro⁶⁹,Gratteri Paola⁹^ORCID

Affiliation:

1. Center of Advanced Research in Bionanoconjugates and Biopolymers, “Petru Poni” Institute of Macromolecular Chemistry of Romanian Academy, 41A Grigore Ghica Voda Alley, Iasi 700487, Romania

2. Research Institute of the University of Bucharest-ICUB, 90 Sos. Panduri, 050663 Bucharest, Romania

3. NMR Laboratory ”Petru Poni” Institute of Macromolecular Chemistry of Romanian Academy, 41A Grigore Ghica Voda Alley, Iasi 700487, Romania

4. Physics of Polymers and Polymeric Materials Department, “Petru Poni” Institute of Macromolecular Chemistry, 41A Grigore Ghica Voda Alley, 700487 Iasi, Romania

5. Department of Chemical and Geological Sciences, University of Cagliari, 09124 Cagliari, Italy

6. Sezione di Scienze Farmaceutiche, NeuroFarba Department, Universita degli Studi di Firenze, Via Ugo Schiff 6, 50019 Sesto Fiorentino, Italy

7. Dipartimento di Chimica “Ugo Schiff”, University of Florence, Via della Lastruccia 3, 50019 Sesto Fiorentino, Florence Italy

8. Department of Pharmacy, “G. d’Annunzio” University of Chieti-Pescara, via dei Vestini 31, 66100 Chieti, Italy

9. NEUROFARBA Department, Pharmaceutical and Nutraceutical Section, Laboratory of Molecular Modeling Cheminformatics & QSAR, University of Florence, Via U. Schiff 6, 50019 Sesto Fiorentino, Firenze Italy

Funder

Research Institute, University of Bucharest

HORIZON EUROPE Framework Programme

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c02190

Reference82 articles.

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2. 3-Hydroxy-1,5-dihydro-2H-pyrrol-2-ones as novel antibacterial scaffolds against methicillin-resistant Staphylococcus aureus

3. The discovery of 1, 3-diamino-7H-pyrrol[3, 2-f]quinazoline compounds as potent antimicrobial antifolates

4. Synthesis and in vitro Evaluation of West Nile Virus Protease Inhibitors Based on the 1,3,4,5‐Tetrasubstituted 1 H ‐Pyrrol‐2(5 H )‐one Scaffold

5. Synthesis and antibacterial activities of some 1-[2-(substituted pyrrol-1-yl)ethyl]-2-methyl-5-nitroimidazole derivatives

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