The Design, Synthesis, and Characterizations of Spore Germination Inhibitors Effective against an Epidemic Strain of Clostridium difficile-Reference-Cited by-同舟云学术

The Design, Synthesis, and Characterizations of Spore Germination Inhibitors Effective against an Epidemic Strain of Clostridium difficile

Published:2018-07-13 Issue:15 Volume:61 Page:6759-6778
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Sharma Shiv K.¹,Yip Christopher²,Esposito Emilio Xavier³,Sharma Prateek V.¹,Simon Matthew P.¹,Abel-Santos Ernesto²,Firestine Steven M.¹^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, 259 Mack Avenue, Detroit, Michigan 48201, United States

2. Department of Chemistry and Biochemistry, University of Nevada at Las Vegas, 4505 South Maryland Parkway, Las Vegas, Nevada 89154, United States

3. exeResearch LLC, 32 University Drive, East Lansing, Michigan 48823, United States

Funder

National Institute of Allergy and Infectious Diseases

Wayne State University

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b00632

Reference86 articles.

1. Clostridium difficile colitis: pathogenesis and host defence

2. Update on the changing epidemiology of Clostridium difficile-associated disease

3. Hypervirulent strains of Clostridium difficile

4. Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)

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