Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors

Author:

Shirai FumiyukiORCID,Tsumura Takeshi,Yashiroda Yoko,Yuki HitomiORCID,Niwa Hideaki,Sato Shin,Chikada Tsubasa,Koda Yasuko,Washizuka Kenichi,Yoshimoto Nobuko,Abe Masako,Onuki Tetsuo,Mazaki Yui,Hirama Chizuko,Fukami Takehiro1,Watanabe Hirofumi,Honma TerukiORCID,Umehara Takashi,Shirouzu Mikako,Okue Masayuki,Kano Yuko,Watanabe Takashi,Kitamura Kouichi,Shitara Eiki,Muramatsu Yukiko2,Yoshida Haruka2,Mizutani Anna2,Seimiya Hiroyuki2,Yoshida Minoru3,Koyama Hiroo

Affiliation:

1. RIKEN Program for Drug Discovery and Medical Technology Platforms, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan

2. Division of Molecular Biotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-ku, Tokyo 135-8850, Japan

3. Department of Biotechnology, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan

Funder

Japan Agency for Medical Research and Development

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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