1. Department of Pharmacology, Juntendo University School of Medicine, Bunkyo-ku, Tokyo 113-8421, Japan
2. Computational Biology
Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Aomi, Koutou-ku, Tokyo 135-0064, Japan
3. Faculty
of Sciences, Hokkaido University, Kita-11, Nishi-8, Kita-ku, Sapporo 060-0812, Japan