Development of a Polo-like Kinase-1 Polo-Box Domain Inhibitor as a Tumor Growth Suppressor in Mice Models-Reference-Cited by-同舟云学术

Development of a Polo-like Kinase-1 Polo-Box Domain Inhibitor as a Tumor Growth Suppressor in Mice Models

Published:2020-11-03 Issue:23 Volume:63 Page:14905-14920
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gunasekaran Pethaiah¹^ORCID,Yim Min Su¹²,Ahn Mija¹,Soung Nak-Kyun³,Park Jung-Eun⁴,Kim Jaehi¹,Bang Geul⁵,Shin Sang Chul⁶,Choi Joonhyeok¹,Kim Minkyoung⁷,Kim Hak Nam¹,Lee Young-Ho¹²^ORCID,Chung Young-Ho⁸,Lee Kyeong⁷^ORCID,EunKyeong Kim Eunice⁶,Jeon Young-Ho⁹,Kim Min Ju¹⁰,Lee Kyeong-Ryoon¹⁰,Kim Bo-Yeon³,Lee Kyung S.⁴^ORCID,Ryu Eun Kyoung¹²^ORCID,Bang Jeong Kyu¹²^ORCID

Affiliation:

1. Division of Magnetic Resonance, Korea Basic Science Institute (KBSI), Ochang, Chung Buk 28119, Republic of Korea

2. Department of Bio-analytical Science, University of Science & Technology, Daejeon 34113, Republic of Korea

3. Anticancer Agent Research Center, Korea Research Institute of Bioscience and Biotechnology, 30 Yeongudanji-ro, Ochang, Cheongwon, Chungbuk 28116, Republic of Korea

4. Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, United States

5. Biomedical Omics Group, Korea Basic Science Institute, Ochang, Chung-Buk 363-883, Republic of Korea

6. Biomedical Research Institute, Korea Institute of Science and Technology, Hwarangno 14-gil 5, Seongbuk-gu, Seoul 02792, Republic of Korea

7. College of Pharmacy, Dongguk University, 52 Dongguk-ro, Ilsandong-gu, Goyang 10320, Republic of Korea

8. Drug & Disease Target Research Team, Korea Basic Science Institute (KBSI), Ochang, Chung Buk 28119, Republic of Korea

9. Laboratory of Biochemistry and Structural Biology, College of Pharmacy, Korea University, Sejong 30019, Republic of Korea

10. Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, 30 Yeongudanji-ro, Ochang, Cheongwon, Chungbuk 28116, Republic of Korea

Funder

Korea Research Institute of Bioscience and Biotechnology

National Research Foundation of Korea

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01451

Reference39 articles.

1. Polo-box domain: a versatile mediator of polo-like kinase function

2. Getting in and out of mitosis with Polo-like kinase-1