Discovery of Novel and Potent N-Methyl-d-aspartate Receptor Positive Allosteric Modulators with Antidepressant-like Activity in Rodent Models-Reference-Cited by-同舟云学术

Discovery of Novel and Potent N-Methyl-d-aspartate Receptor Positive Allosteric Modulators with Antidepressant-like Activity in Rodent Models

Published:2021-05-03 Issue:9 Volume:64 Page:5551-5576
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Li Zhongtang¹,Cai Guanxing¹,Fang Fan¹,Li Wenchao¹,Fan Minghua¹,Lian Jingjing¹,Qiu Yinli²,Xu Xiangqing²,Lv Xuehui¹,Li Yiyan¹,Zheng Ruqiu¹,Wang Yuxi¹,Li Zhongjun¹^ORCID,Zhang Guisen³,Liu Zhenming¹^ORCID,Huang Zhuo¹^ORCID,Zhang Liangren¹^ORCID

Affiliation:

1. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China

2. Jiangsu Nhwa Pharmaceutical Co., Ltd. 69 Democratic South Road, Xuzhou, Jiangsu 221116, China

3. Jiangsu Key Laboratory of Marine Biological Resources and Environment, Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, School of Pharmacy, Jiangsu Ocean University, Lianyungang 222005, China

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c02018

Reference43 articles.

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2. Neural basis of major depressive disorder: Beyond monoamine hypothesis