Synthesis and Evaluation of 4-Hydroxycoumarin Imines as Inhibitors of Class II Myosins-Reference-Cited by-同舟云学术

Synthesis and Evaluation of 4-Hydroxycoumarin Imines as Inhibitors of Class II Myosins

Published:2020-09-07 Issue:19 Volume:63 Page:11131-11148
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Brawley Jhonnathan¹,Etter Emily²,Heredia Dante³,Intasiri Amarawan¹⁴,Nennecker Kyle²,Smith Joshua²,Welcome Brandon M.²,Brizendine Richard K.²,Gould Thomas W.³,Bell Thomas W.¹^ORCID,Cremo Christine²

Affiliation:

1. Department of Chemistry, University of Nevada, Reno, Nevada 89557-0216, United States

2. Department of Pharmacology, University of Nevada, Reno School of Medicine, Reno, Nevada 89557-0318, United States

3. Department of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, Reno, Nevada 89557-0352, United States

4. Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand

Funder

National Institute of Neurological Disorders and Stroke

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01062

Reference84 articles.

1. Myosin Structure, Allostery, and Mechano-Chemistry

2. Myosin isoforms and the mechanochemical cross-bridge cycle

3. Review: The ATPase mechanism of myosin and actomyosin

4. A myosin II mutation uncouples ATPase activity from motility and shortens step size

5. Nemaline myopathy with stiffness and hypertonia associated with an ACTA1 mutation

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