A Novel Potent and Highly Specific Inhibitor against Influenza Viral N1–N9 Neuraminidases: Insight into Neuraminidase–Inhibitor Interactions

Author:

Sriwilaijaroen Nongluk12,Magesh Sadagopan,Imamura Akihiro,Ando Hiromune3,Ishida Hideharu,Sakai Miho,Ishitsubo Erika,Hori Takanori,Moriya Setsuko4,Ishikawa Takeshi,Kuwata Kazuo,Odagiri Takato5,Tashiro Masato5,Hiramatsu Hiroaki2,Tsukamoto Kenji6,Miyagi Taeko4,Tokiwa Hiroaki,Kiso Makoto3,Suzuki Yasuo2

Affiliation:

1. Department of Preclinical Sciences, Faculty of Medicine, Thammasat University, Pathumthani 12120, Thailand

2. Health Science Hills, College of Life and Health Sciences, Chubu University, Aichi 487-8501, Japan

3. Institute for Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University, Kyoto 606-8501, Japan

4. Division of Cancer Glycosylation Research, Institute of Molecular Biomembrane and Glycobiology, Tohoku Pharmaceutical University, Sendai 981-8558, Japan

5. Influenza Virus Research Center, National Institute of Infectious Diseases, Tokyo 208-0011, Japan

6. Research Team for Zoonotic Diseases, National Institute of Animal Health, Ibaraki 305-0856, Japan

Funder

Ministry of Education, Culture, Sports, Science, and Technology

National Research Council of Thailand

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference65 articles.

1. A distinct lineage of influenza A virus from bats

2. New World Bats Harbor Diverse Influenza A Viruses

3. World Health Organization (WHO). Avian influenza in humans. Influenza virus activity in the world.http://www.who.int/influenza/gisrs_laboratory/updates/summaryreport_20131111/en/(accessed Oct 12, 2015) .

4. Molecular basis of the structure and function of H1 hemagglutinin of influenza virus

5. Molecular Basis of a Pandemic of Avian-Type Influenza Virus

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