Discovery of 4-Amino-8-quinoline Carboxamides as Novel, Submicromolar Inhibitors of NAD-Hydrolyzing Enzyme CD38-Reference-Cited by-同舟云学术

Discovery of 4-Amino-8-quinoline Carboxamides as Novel, Submicromolar Inhibitors of NAD-Hydrolyzing Enzyme CD38

Published:2015-08-24 Issue:17 Volume:58 Page:7021-7056
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Becherer J. David¹,Boros Eric E.¹,Carpenter Tiffany Y.¹,Cowan David J.¹,Deaton David N.¹,Haffner Curt D.¹,Jeune Michael R.¹,Kaldor Istvan W.¹,Poole J. Chuck¹,Preugschat Frank¹,Rheault Tara R.¹,Schulte Christie A.¹,Shearer Barry G.¹,Shearer Todd W.¹,Shewchuk Lisa M.¹,Smalley Terrence L.¹,Stewart Eugene L.¹,Stuart J. Darren¹,Ulrich John C.¹

Affiliation:

1. GlaxoSmithKline Research and Development, 5 Moore Drive, P.O. Box 13398, Research Triangle Park, North Carolina 27709, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b00992

Reference24 articles.

1. Discrete stages of human intrathymic differentiation: Analysis of normal thymocytes and leukemic lymphoblasts of T-cell lineage

2. Chromosome assignment of monoclonal antibody-defined determinants on human leukemic cells

3. CD38 and CD157: A long journey from activation markers to multifunctional molecules

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