Fragment-Linking Approach Using 19F NMR Spectroscopy To Obtain Highly Potent and Selective Inhibitors of β-Secretase
Author:
Affiliation:
1. Therapeutic Discovery, Amgen, Inc. One Amgen Center Drive, Thousand Oaks, California 91320, United States
Funder
Basic Energy Sciences
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b01917
Reference33 articles.
1. Fragment-based lead discovery grows up
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5. Fragment Based Drug Discovery: Practical Implementation Based on 19F NMR Spectroscopy
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