Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3-Reference-Cited by-同舟云学术

Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3

Published:2015-04-13 Issue:8 Volume:58 Page:3611-3625
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Boyd Scott¹,Brookfield Joanna L.²,Critchlow Susan E.¹,Cumming Iain A.²,Curtis Nicola J.¹,Debreczeni Judit¹,Degorce Sébastien L.¹,Donald Craig¹,Evans Nicola J.³,Groombridge Sam¹,Hopcroft Philip¹,Jones Neil P.³,Kettle Jason G.¹,Lamont Scott¹,Lewis Hilary J.¹,MacFaull Philip¹,McLoughlin Sheila B.²,Rigoreau Laurent J. M.²,Smith James M.²,St-Gallay Steve¹,Stock Julie K.³,Turnbull Andrew P.³,Wheatley Edward R.³,Winter Jon¹,Wingfield Jonathan¹

Affiliation:

1. Oncology Innovative Medicines Unit, AstraZeneca, 35S47 Mereside, Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom

2. CRT Discovery Laboratories, Jonas Webb Building (B910), Babraham Research Campus, Cambridge, CB22 3AT, United Kingdom

3. CRT Discovery Laboratories, Wolfson Institute for Biomedical Research, University College London, The Cruciform Building, Gower Street, London WC1E 6BT, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b00352

Reference17 articles.

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