Potent Inhibition of SARS-CoV-2 nsp14 <i>N</i>7-Methyltransferase by Sulfonamide-Based Bisubstrate Analogues-Reference-Cited by-同舟云学术

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Potent Inhibition of SARS-CoV-2 nsp14 N7-Methyltransferase by Sulfonamide-Based Bisubstrate Analogues

Published:2022-04-19 Issue:8 Volume:65 Page:6231-6249
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ahmed-Belkacem Rostom¹,Hausdorff Marcel¹,Delpal Adrien²,Sutto-Ortiz Priscila²^ORCID,Colmant Agathe M. G.³^ORCID,Touret Franck³,Ogando Natacha S.⁴,Snijder Eric J.⁴,Canard Bruno²,Coutard Bruno³,Vasseur Jean-Jacques¹^ORCID,Decroly Etienne²,Debart Françoise¹^ORCID

Affiliation:

1. IBMM, University of Montpellier, CNRS, ENSCM, 34293 Montpellier, cedex 5, France

2. AFMB, University of Aix-Marseille, CNRS, 13288 Marseille, cedex 9, France

3. IHU Méditerranée Infection, Unité Virus Emergents, University of Aix-Marseille, IRD 190, INSERM 1207, 13005 Marseille, France

4. Department of Medical Microbiology, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands

Funder

Agence Nationale de la Recherche

H2020 Health

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c00120

Reference37 articles.

1. Characterization of a Novel Coronavirus Associated with Severe Acute Respiratory Syndrome

2. SARS and MERS: recent insights into emerging coronaviruses

3. The evolution of nucleoside analogue antivirals: A review for chemists and non-chemists. Part 1: Early structural modifications to the nucleoside scaffold

4. The evolution of antiviral nucleoside analogues: A review for chemists and non-chemists. Part II: Complex modifications to the nucleoside scaffold

5. Biochemical principles and inhibitors to interfere with viral capping pathways

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3. How Much Potential Do Nucleoside Analogs Offer to Combat Human Corona Viruses?;Organics;2024-05-08

4. Exploring the Efficacy of Noncovalent SARS‐CoV‐2 Main Protease Inhibitors: A Computational Simulation Analysis Study;Chemistry & Biodiversity;2024-04-16

5. First report on the QSAR modelling and multistep virtual screening of the inhibitors of nonstructural protein Nsp14 of SARS-CoV-2: Reducing unnecessary chemical synthesis and experimental tests;Arabian Journal of Chemistry;2024-03

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