First-in-Class Allosteric Inhibitors of DNMT3A Disrupt Protein–Protein Interactions and Induce Acute Myeloid Leukemia Cell Differentiation-Reference-Cited by-同舟云学术

First-in-Class Allosteric Inhibitors of DNMT3A Disrupt Protein–Protein Interactions and Induce Acute Myeloid Leukemia Cell Differentiation

Published:2022-07-22 Issue:15 Volume:65 Page:10554-10566
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Sandoval Jonathan E.¹²^ORCID,Ramabadran Raghav³⁴⁵,Stillson Nathaniel¹,Sarah Letitia⁶,Fujimori Danica Galonić⁶^ORCID,Goodell Margaret A.³⁴,Reich Norbert¹^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106-9510, United States

2. Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, California 93106-9510, United States

3. Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, Texas 77030, United States

4. Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, United States

5. Interdepartmental Program in Integrative Molecular and Biomedical Sciences, Baylor College of Medicine, Houston, Texas 77030, United States

6. Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, California 94158, United States

Funder

Division of Chemistry

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c00725

Reference84 articles.

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