High-Contrast PET Imaging with [<sup>18</sup>F]NT160, a Class-IIa Histone Deacetylase Probe for In Vivo Imaging of Epigenetic Machinery in the Central Nervous System-Reference-Cited by-同舟云学术

High-Contrast PET Imaging with [¹⁸F]NT160, a Class-IIa Histone Deacetylase Probe for In Vivo Imaging of Epigenetic Machinery in the Central Nervous System

Published:2023-04-17 Issue:8 Volume:66 Page:5611-5621
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Turkman Nashaat¹²³^ORCID,Xu Sulan¹²,Huang Chun-Han¹²³,Eyermann Christopher²⁴,Salino Julia¹²,Khan Palwasha¹²

Affiliation:

1. Stony Brook Cancer Center, Stony Brook, Long Island, New York 11794, United States

2. Department of Radiology, School of Medicine, Stony Brook University, Long Island, New York 11794, United States

3. Department of Biomedical Engineering, Stony Brook University, Long Island, New York 11794, United States

4. Department of Surgery, School of Medicine, Stony Brook University, Long Island, New York 11794, United States

Funder

National Institute on Aging

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c02064

Reference40 articles.

1. Class IIa histone deacetylases affect neuronal remodeling and functional outcome after stroke

2. Pharmacological Inhibition of Histone Deacetylases by Suberoylanilide Hydroxamic Acid Specifically Alters Gene Expression and Reduces Ischemic Injury in the Mouse Brain

3. Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and heat shock protein induction

4. Histone Deacetylase Inhibitors Exhibit Anti-Inflammatory and Neuroprotective Effects in a Rat Permanent Ischemic Model of Stroke: Multiple Mechanisms of Action

5. Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

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