Discovery of RMC-5552, a Selective Bi-Steric Inhibitor of mTORC1, for the Treatment of mTORC1-Activated Tumors-Reference-Cited by-同舟云学术

Discovery of RMC-5552, a Selective Bi-Steric Inhibitor of mTORC1, for the Treatment of mTORC1-Activated Tumors

Published:2022-12-19 Issue:1 Volume:66 Page:149-169
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Burnett G. Leslie¹^ORCID,Yang Yu C.¹,Aggen James B.¹^ORCID,Pitzen Jennifer¹,Gliedt Micah K.¹,Semko Chris M.¹,Marquez Abby¹,Evans James W.¹,Wang Gang¹,Won Walter S.¹,Tomlinson Aidan C. A.¹,Kiss Gert¹,Tzitzilonis Christos¹,Thottumkara Arun P.¹,Cregg James¹,Mellem Kevin T.¹,Choi Jong S.¹,Lee Julie C.¹,Zhao Yongyuan¹,Lee Bianca J.¹,Meyerowitz Justin G.¹,Knox John E.¹,Jiang Jingjing¹,Wang Zhican¹,Wildes David¹,Wang Zhengping¹,Singh Mallika¹,Smith Jacqueline A. M.¹,Gill Adrian L.¹

Affiliation:

1. Revolution Medicines, Incorporated, Redwood City, California 94063, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01658

Reference101 articles.

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