<i>N</i>-Phenyl-1-(phenylsulfonyl)-1<i>H</i>-1,2,4-triazol-3-amine as a New Class of HIV-1 Non-nucleoside Reverse Transcriptase Inhibitor-Reference-Cited by-同舟云学术

N-Phenyl-1-(phenylsulfonyl)-1H-1,2,4-triazol-3-amine as a New Class of HIV-1 Non-nucleoside Reverse Transcriptase Inhibitor

Published:2023-05-02 Issue:9 Volume:66 Page:6193-6217
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lane Thomas¹^ORCID,Makarov Vadim²,Nelson Julie A. E.³,Meeker Rick B.⁴,Sanna Giuseppina⁵,Riabova Olga²,Kazakova Elena²,Monakhova Natalia²,Tsedilin Andrey²,Urbina Fabio¹,Jones Thane¹,Suchy Ashley³,Ekins Sean¹^ORCID

Affiliation:

1. Collaborations Pharmaceuticals Inc., 840 Main Campus Drive, Lab 3510, Raleigh, North Carolina 27606, United States

2. Research Center of Biotechnology RAS, Leninsky Prospekt 33-2, 119071, Moscow 119071, Russia

3. Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina 27599, United States

4. Department of Neurology, University of North Carolina, Chapel Hill, North Carolina 27599, United States

5. Department of Biomedical Science, University of Cagliari, Monserrato 09042, Italy

Funder

National Institute of Environmental Health Sciences

National Institute of Neurological Disorders and Stroke

Center for AIDS Research, University of North Carolina at Chapel Hill

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c02055

Reference106 articles.

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2. Anon. Unaids. Global hiv & aids statistics─2020 fact sheet. https://www.unaids.org/en/resources/fact-sheet (accessed Mar 29, 2023).

3. UNICEF. Global and regional trends. https://data.unicef.org/topic/hivaids/global-regional-trends/ (accessed Mar 29, 2023).

4. CDC. Statistics overview. https://www.cdc.gov/hiv/statistics/overview/index.htmL (accessed Mar 29, 2023).

5. Highly Active Antiretroviral Therapy Decreases Mortality and Morbidity in Patients with Advanced HIV Disease

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