Synthesis, Optimization, and Structure–Activity Relationships of Imidazo[1,2-<i>a</i>]pyrimidines as Inhibitors of Group 2 Influenza A Viruses-Reference-Cited by-同舟云学术

Synthesis, Optimization, and Structure–Activity Relationships of Imidazo[1,2-a]pyrimidines as Inhibitors of Group 2 Influenza A Viruses

Published:2022-10-19 Issue:20 Volume:65 Page:14104-14120
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Alqarni Saad¹²^ORCID,Cooper Laura³,Galvan Achi Jazmin³^ORCID,Bott Ryan³,Sali Veeresh Kumar⁴,Brown Andrew¹,Santarsiero Bernard D.¹^ORCID,Krunic Aleksej¹,Manicassamy Balaji⁴^ORCID,Peet Norton P.⁵,Zhang Pin³^ORCID,Thatcher Gregory R. J.⁶^ORCID,Gaisina Irina N.¹⁵^ORCID,Rong Lijun³⁵,Moore Terry W.¹⁷^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago (UIC), Chicago, Illinois60612, United States

2. Department of Pharmaceutical Chemistry, College of Pharmacy, University of Ha’il, Ha’il81442, Saudi Arabia

3. Department of Microbiology and Immunology, University of Illinois at Chicago, Chicago, Illinois60612, United States

4. Department of Microbiology and Immunology, University of Iowa, Iowa City, Iowa52242, United States

5. Chicago BioSolutions Inc., Chicago, Illinois60612, United States

6. Department of Pharmacology and Toxicology, R. Ken Coit College of Pharmacy, University of Arizona, Tucson, Arizona85721, United States

7. UI Cancer Center, University of Illinois at Chicago, Chicago, Illinois60612, United States

Funder

National Institute of Allergy and Infectious Diseases

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01329

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