Development of Alkylated Hydrazides as Highly Potent and Selective Class I Histone Deacetylase Inhibitors with T cell Modulatory Properties-Reference-Cited by-同舟云学术

Development of Alkylated Hydrazides as Highly Potent and Selective Class I Histone Deacetylase Inhibitors with T cell Modulatory Properties

Published:2022-11-30 Issue:24 Volume:65 Page:16313-16337
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Sun Ping¹,Wang Jing²,Khan Khadija S.²³,Yang Weiqin²,Ng Billy Wai-Lung³^ORCID,Ilment Nikita¹^ORCID,Zessin Matthes¹,Bülbül Emre F.¹,Robaa Dina¹,Erdmann Frank¹,Schmidt Matthias¹,Romier Christophe⁴^ORCID,Schutkowski Mike⁵^ORCID,Cheng Alfred Sze-Lok²,Sippl Wolfgang¹^ORCID

Affiliation:

1. Department of Medicinal Chemistry, Institute of Pharmacy, Martin-Luther University of Halle-Wittenberg, 06120 Halle/Saale, Germany

2. School of Biomedical Sciences, The Chinese University of Hong Kong, 999077 Hong Kong SAR, China

3. School of Pharmacy, The Chinese University of Hong Kong, 999077 Hong Kong SAR, China

4. Département de Biologie Structurale Intégrative, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg, CNRS, INSERM, 67404 Illkirch Cedex, France

5. Department of Enzymology, Institute of Biotechnology, Martin-Luther University of Halle-Wittenberg, 06120 Halle/Saale, Germany

Funder

Research Grants Council, University Grants Committee

Deutsche Forschungsgemeinschaft

Li Ka Shing Foundation

China Scholarship Council

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c01132