Novel 15-Lipoxygenase-1 Inhibitor Protects Macrophages from Lipopolysaccharide-Induced Cytotoxicity-Reference-Cited by-同舟云学术

Novel 15-Lipoxygenase-1 Inhibitor Protects Macrophages from Lipopolysaccharide-Induced Cytotoxicity

Published:2019-04-09 Issue:9 Volume:62 Page:4624-4637
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Guo Hao,Verhoek Iris C.,Prins Gerian G. H.,van der Vlag Ramon¹^ORCID,van der Wouden Petra E.,van Merkerk Ronald,Quax Wim J.,Olinga Peter,Hirsch Anna K. H.¹²³,Dekker Frank J.^ORCID

Affiliation:

1. Department of Chemical Biology 2, Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands

2. Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)−Helmholtz Centre for Infection Research (HZI), Department of Drug Design and Optimization, Campus Building E8.1, 66123 Saarbrücken, Germany

3. Department of Pharmacy, Saarland University, 66123 Saarbrücken, Germany

Funder

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

China Scholarship Council

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

http://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00212

Reference46 articles.

1. Regulated cell death and inflammation: an auto-amplification loop causes organ failure