Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase-Reference-Cited by-同舟云学术

Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase

Published:2019-04-19 Issue:9 Volume:62 Page:4483-4499
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Crespo Roberto A.¹,Dang Qun²,Zhou Nian E.¹,Guthrie Liam M.³,Snavely Thomas C.¹,Dong Wen¹,Loesch Kimberly A.¹,Suzuki Takao⁴,You Lanying⁴,Wang Wei⁴,O’Malley Theresa⁵,Parish Tanya⁵^ORCID,Olsen David B.²,Sacchettini James C.¹^ORCID

Affiliation:

1. Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas 77843, United States

2. Merck Sharp Dohme Corporation, West Point Pennsylvania 19486, United States

3. College of Medicine, Texas A&M University Health Science Center, Bryan, Texas 77807, United States

4. WuXi AppTec, 288 Fute Zhong Road, Shanghai 200131, China

5. TB Discovery Research, Infectious Disease Research Institute, 1616 Eastlake Avenue E, Seattle, Washington 98102, United States

Funder

National Institute of Allergy and Infectious Diseases

Bill and Melinda Gates Foundation

Welch Foundation

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

http://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00020

Reference51 articles.

1. WHO. Global Tuberculosis Report, 2016.

2. Purine Salvage Pathway in Mycobacterium tuberculosis

3. Pyrimidine Salvage Pathway in Mycobacterium tuberculosis

4. Identification and Characterization of a Unique Adenosine Kinase from Mycobacterium tuberculosis

5. High Resolution Crystal Structures of Mycobacterium tuberculosis Adenosine Kinase

Cited by 11 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Structure of YdjH from Acinetobacter baumannii revealed an active site of YdjH family sugar kinase;Biochemical and Biophysical Research Communications;2023-07

2. Recent Developments in Medicinal and In Silico Applications of Imidazopyridine Derivatives: Special Emphasis on Malaria, Trypanosomiasis, and Tuberculosis;Chemistry Africa;2022-09-10

3. New Approach to Biologically Active Indolo[2,3‐ b ]quinoxaline Derivatives through Intramolecular Oxidative Cyclodehydrogenation;ChemistrySelect;2022-05-10

4. An Outline of the Latest Crystallographic Studies on Inhibitor-Enzyme Complexes for the Design and Development of New Therapeutics against Tuberculosis;Molecules;2021-11-23

5. Application of diazonium chemistry in purine modifications: A focused review;Journal of Heterocyclic Chemistry;2021-08-09