C-6α- vs C-7α-Substituted Steroidal Aromatase Inhibitors: Which Is Better? Synthesis, Biochemical Evaluation, Docking Studies, and Structure–Activity Relationships-Reference-Cited by-同舟云学术

C-6α- vs C-7α-Substituted Steroidal Aromatase Inhibitors: Which Is Better? Synthesis, Biochemical Evaluation, Docking Studies, and Structure–Activity Relationships

Published:2019-03-09 Issue:7 Volume:62 Page:3636-3657
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Roleira Fernanda M. F.¹²^ORCID,Varela Carla¹²,Amaral Cristina³,Costa Saul C.¹,Correia-da-Silva Georgina³,Moraca Federica⁴⁵⁶,Costa Giosuè⁴⁶^ORCID,Alcaro Stefano⁴⁶,Teixeira Natércia A. A.³,Tavares da Silva Elisiário J.¹²^ORCID

Affiliation:

1. Laboratory of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal

2. CIEPQPF Centre for Chemical Processes Engineering and Forest Products, University of Coimbra, 3030-790 Coimbra, Portugal

3. UCIBIO.REQUIMTE, Laboratory of Biochemistry, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal

4. Laboratorio di Chimica Farmaceutica, Dipartimento di Scienze della Salute, Università Magna Græcia di Catanzaro, 88100 Catanzaro, Italy

5. Department of Pharmacy, University of Naples “Federico II”, via D. Montesano 49, 80131, Naples, Italy

6. Net4Science Academic Spin-Off, “Magna Græcia” University of Catanzaro, “S. Venuta”, Catanzaro, Italy

Funder

Funda??o para a Ci?ncia e a Tecnologia

European Regional Development Fund

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00157

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