Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2′-Oxidase-Reference-Cited by-同舟云学术

Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-d-ribofuranose 2′-Oxidase

Published:2019-08-08 Issue:17 Volume:62 Page:8115-8139
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Karabanovich Galina¹,Dušek Jan¹,Savková Karin²,Pavliš Oto³,Pávková Ivona⁴,Korábečný Jan⁴⁵^ORCID,Kučera Tomáš⁴,Kočová Vlčková Hana¹,Huszár Stanislav²,Konyariková Zuzana²,Konečná Klára¹,Jand’ourek Ondřej¹,Stolaříková Jiřina⁶,Korduláková Jana²,Vávrová Kateřina¹,Pávek Petr¹,Klimešová Věra¹,Hrabálek Alexandr¹,Mikušová Katarína²,Roh Jaroslav¹^ORCID

Affiliation:

1. Faculty of Pharmacy in Hradec Králové, Charles University, Akademika Heyrovského 1203, 50005 Hradec Králové, Czech Republic

2. Faculty of Natural Sciences, Department of Biochemistry, Comenius University in Bratislava, Mlynská Dolina, Ilkovičova 6, 842 15 Bratislava, Slovakia

3. Biological Defense Department, Military Health Institute, 561 64 Techonin, Czech Republic

4. Faculty of Military Health Sciences, University of Defence, Třebešská 1575, 50005 Hradec Králové, Czech Republic

5. Biomedical Research Center, University Hospital Hradec Králové, Sokolska 581, 500 05 Hradec Králové, Czech Republic

6. Department of Bacteriology and Mycology, Regional Institute of Public Health, Partyzánské náměstí 7, 70200 Ostrava, Czech Republic

Funder

European Regional Development Fund

Agent?ra Ministerstva ?kolstva, vedy, v?skumu a ?portu SR

Ministerstvo Zdravotnictv? Cesk? Republiky

Univerzita Karlova v Praze

Agent?ra na Podporu V?skumu a V?voja

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00912

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