Discovery and Biological Evaluations of Halogenated 2,4-Diphenyl Indeno[1,2-b]pyridinol Derivatives as Potent Topoisomerase IIα-Targeted Chemotherapeutic Agents for Breast Cancer-Reference-Cited by-同舟云学术

Discovery and Biological Evaluations of Halogenated 2,4-Diphenyl Indeno[1,2-b]pyridinol Derivatives as Potent Topoisomerase IIα-Targeted Chemotherapeutic Agents for Breast Cancer

Published:2019-08-09 Issue:17 Volume:62 Page:8194-8234
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kadayat Tara Man¹²,Park Seojeong³,Shrestha Aarajana¹,Jo Hyunji³,Hwang Soo-Yeon³,Katila Pramila¹,Shrestha Ritina¹,Nepal Mahesh Raj¹,Noh Keumhan¹,Kim Sang Kyoon⁴,Koh Woo-Suk⁴,Kim Kil Soo⁴⁵,Jeon Yong Hyun⁴^ORCID,Jeong Tae Cheon¹,Kwon Youngjoo³,Lee Eung-Seok¹^ORCID

Affiliation:

1. College of Pharmacy, Yeungnam University, Gyeongsan 38541, Republic of Korea

2. New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41061, Republic of Korea

3. College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 120-750, Republic of Korea

4. Laboratory Animal Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu 41061, Republic of Korea

5. College of Veterinary Medicine, Kyungpook National University, Daegu 41566, Republic of Korea

Funder

National Research Foundation of Korea

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00970

Reference34 articles.

1. Drugs and Cancer

2. Cellular roles of DNA topoisomerases: a molecular perspective

3. Origin and evolution of DNA topoisomerases

4. All tangled up: how cells direct, manage and exploit topoisomerase function

5. Major Contributions towards Finding a Cure for Cancer through Chemotherapy: A Historical Review

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