Discovery of a Furanopyrimidine-Based Epidermal Growth Factor Receptor Inhibitor (DBPR112) as a Clinical Candidate for the Treatment of Non-Small Cell Lung Cancer-Reference-Cited by-同舟云学术

Discovery of a Furanopyrimidine-Based Epidermal Growth Factor Receptor Inhibitor (DBPR112) as a Clinical Candidate for the Treatment of Non-Small Cell Lung Cancer

Published:2019-09-27 Issue:22 Volume:62 Page:10108-10123
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lin Shu-Yu¹,Chang Hsu Yung¹,Peng Yi-Hui¹,Ke Yi-Yu¹,Lin Wen-Hsing¹,Sun Hsu-Yi¹,Shiao Hui-Yi¹,Kuo Fu-Ming¹,Chen Pei-Yi¹,Lien Tzu-Wen¹,Chen Chun-Hwa¹,Chu Chang-Ying¹,Wang Sing-Yi¹,Yeh Kai-Chia¹,Chen Ching-Ping¹,Hsu Tsu-An¹,Wu Su-Ying¹^ORCID,Yeh Teng-Kuang¹,Chen Chiung-Tong¹,Hsieh Hsing-Pang¹²^ORCID

Affiliation:

1. Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, 35 Keyan Road, Zhunan, Miaoli County 35053, Taiwan, ROC

2. Department of Chemistry, National Tsing Hua University, Hsinchu 30013, Taiwan, ROC

Funder

Ministry of Education

National Health Research Institutes

Ministry of Science and Technology, Taiwan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00722

Reference61 articles.

1. World Health Organization (WHO). Statistics Reports for Lung Cancer. http://www.who.int/news-room/fact-sheets/detail/cancer (accessed Feb 1, 2018).

2. Global cancer statistics

3. Epidermal growth factor receptor mutations in lung cancer

4. A Prospective, Molecular Epidemiology Study of EGFR Mutations in Asian Patients with Advanced Non–Small-Cell Lung Cancer of Adenocarcinoma Histology (PIONEER)

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