Oxidation of Human Growth Hormone by Oxygen-Centered Radicals: Formation of Leu-101 Hydroperoxide and Tyr-103 Oxidation Products
Author:
Affiliation:
1. Department of Pharmaceutical Chemistry, University of Kansas, Lawrence, Kansas 66047, United States
2. Late Stage Pharmaceutical Development, Genentech Inc., South San Francisco, California 94080, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/mp3001028
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1. Stability of Protein Pharmaceuticals: An Update
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5. Polysorbates 20 and 80 Used in the Formulation of Protein Biotherapeutics: Structure and Degradation Pathways
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