1-Amino-4-benzylphthalazines as Orally Bioavailable Smoothened Antagonists with Antitumor Activity-Reference-Cited by-同舟云学术

1-Amino-4-benzylphthalazines as Orally Bioavailable Smoothened Antagonists with Antitumor Activity

Published:2009-05-26 Issue:13 Volume:52 Page:3954-3968
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Miller-Moslin Karen¹,Peukert Stefan¹,Jain Rishi K.¹,McEwan Michael A.¹,Karki Rajesh¹,Llamas Luis¹,Yusuff Naeem¹,He Feng¹,Li Yanhong¹,Sun Yingchuan¹,Dai Miao¹,Perez Lawrence¹,Michael Walter¹,Sheng Tao¹,Lei Huangshu¹,Zhang Rui¹,Williams Juliet¹,Bourret Aaron¹,Ramamurthy Arun¹,Yuan Jing¹,Guo Ribo¹,Matsumoto Melissa¹,Vattay Anthony¹,Maniara Wieslawa¹,Amaral Adam¹,Dorsch Marion¹,Kelleher Joseph F.¹

Affiliation:

1. Departments of Global Discovery Chemistry, Developmental and Molecular Pathways, Oncology, and Metabolism and Pharmacokinetics, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 01239

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm900309j

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