A Novel Bromine-Containing Paroxetine Analogue Provides Mechanistic Clues for Binding Ambiguity at the Central Primary Binding Site of the Serotonin Transporter

Author:

Slack Rachel D.1,Abramyan Ara M.1,Tang Helen1,Meena Sitaram2,Davis Bruce A.2,Bonifazi Alessandro1ORCID,Giancola JoLynn B.1,Deschamps Jeffrey R.3,Naing Sett1,Yano Hideaki1,Singh Satinder K.2ORCID,Newman Amy Hauck1ORCID,Shi Lei1ORCID

Affiliation:

1. Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse - Intramural Research Program, National Institutes of Health, 333 Cassell Drive, Baltimore, Maryland 21224, United States

2. Department of Cellular and Molecular Physiology, Yale University School of Medicine, 333 Cedar Street, New Haven, Connecticut 06520, United States

3. Naval Research Laboratory, Code 6030, 4555 Overlook Avenue, Washington D. C. 20375, United States

Funder

Alfred P. Sloan Foundation

Brain and Behavior Research Foundation

National Institutes of Health

Goodman-Gilman Yale Scholar Award

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

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