HSP90 Inhibitor, NVP-AUY922, Improves Myelination in Vitro and Supports the Maintenance of Myelinated Axons in Neuropathic Mice-Reference-Cited by-同舟云学术

HSP90 Inhibitor, NVP-AUY922, Improves Myelination in Vitro and Supports the Maintenance of Myelinated Axons in Neuropathic Mice

Published:2019-04-24 Issue:6 Volume:10 Page:2890-2902
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Chittoor-Vinod Vinita G.¹,Bazick Hannah¹,Todd Adrian G.²,Falk Darin²,Morelli Kathryn H.³⁴,Burgess Robert W.³⁴,Foster Thomas C.¹,Notterpek Lucia¹^ORCID

Affiliation:

1. Departments of Neuroscience and Neurology, College of Medicine, McKnight Brain Institute, 1149 Newell Drive, Box 100244, Gainesville, Florida 32610-0244, United States

2. Department of Pediatrics, Powell Gene Therapy Center, University of Florida, Gainesville, Florida 32611, United States

3. The Graduate School of Biomedical Science and Engineering, University of Maine, Orono, Maine 04469, United States

4. The Jackson Laboratory, Bar Harbor, Maine 04609, United States

Funder

U.S. Department of Health and Human Services

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

http://pubs.acs.org/doi/pdf/10.1021/acschemneuro.9b00105

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5. Hsp110 Is a Bona Fide Chaperone Using ATP to Unfold Stable Misfolded Polypeptides and Reciprocally Collaborate with Hsp70 to Solubilize Protein Aggregates

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