A Pentacyclic Triterpene from Ligustrum lucidum Targets γ-Secretase

Author:

Luo Wenjie1,Ip Fanny C. F.234ORCID,Fu Guangmiao2,Cheung Kit2ORCID,Tian Yuan1,Hu Yueqing2,Sinha Anjana1,Cheng Elaine Y. L.2,Wu Xianzhong5,Bustos Victor1,Greengard Paul1,Li Yue-Ming5ORCID,Sinha Subhash C.1ORCID,Ip Nancy Y.234ORCID

Affiliation:

1. Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York 10065, United States

2. Division of Life Science, State Key Laboratory of Molecular Neuroscience, and Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Clear Water Bay Road, Kowloon, Hong Kong, China

3. Hong Kong Center for Neurodegenerative Diseases, Hong Kong Science Park, Hong Kong, China

4. Guangdong Provincial Key Laboratory of Brain Science, Disease and Drug Development, Shenzhen−Hong Kong Institute of Brain Science, HKUST Shenzhen Research Institute, Shenzhen, Guangdong, China 518057

5. Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States

Funder

Guangdong Science and Technology Department

U.S. Department of Health and Human Services

Research Grants Council, University Grants Committee

Ministry of Science and Technology of the People's Republic of China

Government of Guangdong Province

Innovation and Technology Commission

Fisher Center for Alzheimer's Research Foundation

JPB Foundation

Shenzhen Knowledge Innovation Program

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

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