Discovery of a Small-Molecule Modulator of the Autophagy-Lysosome Pathway That Targets Lamin A/C and LAMP1, Induces Autophagic Flux, and Affects Lysosome Positioning in Neurons-Reference-Cited by-同舟云学术

Discovery of a Small-Molecule Modulator of the Autophagy-Lysosome Pathway That Targets Lamin A/C and LAMP1, Induces Autophagic Flux, and Affects Lysosome Positioning in Neurons

Published:2023-12-09 Issue:24 Volume:14 Page:4363-4382
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Hippman Ryan S.¹,Snead Amanda M.²,Petros Zoe A.¹,Korkmaz-Vaisys Melissa A.¹^ORCID,Patel Sruchi²,Sotelo Daniel¹,Dobria Andrew¹^ORCID,Salkovski Maryna¹,Nguyen Thu T. A.¹,Linares Ricardo²,Cologna Stephanie M.¹^ORCID,Gowrishankar Swetha²,Aldrich Leslie N.¹^ORCID

Affiliation:

1. Department of Chemistry, College of Liberal Arts and Sciences, University of Illinois Chicago, 845 W. Taylor Street, Chicago, Illinois 60607, United States

2. Department of Anatomy and Cell Biology, College of Medicine, University of Illinois Chicago, 808 S. Wood Street, Chicago, Illinois 60612, United States

Funder

Dr. Ralph and Marian Falk Medical Research Trust

National Center for Advancing Translational Sciences

National Institute of Neurological Disorders and Stroke

National Institute on Aging

Wolverine Foundation

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.3c00573