Identification of 2-({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)tricyclo[3.3.1.13,7]decane-2-carboxylic Acid (NTRC-844) as a Selective Antagonist for the Rat Neurotensin Receptor Type 2-Reference-Cited by-同舟云学术

Identification of 2-({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)tricyclo[3.3.1.13,7]decane-2-carboxylic Acid (NTRC-844) as a Selective Antagonist for the Rat Neurotensin Receptor Type 2

Published:2016-07-13 Issue:9 Volume:7 Page:1225-1231
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Thomas James B.¹,Vivancos Mélanie²,Giddings Angela M.¹,Wiethe Robert W.¹,Warner Keith R.¹,Murza Alexandre²,Besserer-Offroy Élie²,Longpré Jean-Michel²,Runyon Scott P.¹,Decker Ann M.¹,Gilmour Brian P.¹,Sarret Philippe²

Affiliation:

1. Center for Drug Discovery, RTI International, P.O. Box 12194, Research Triangle Park, North Carolina 27709, United States

2. Department of Pharmacology and Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, 3001, 12th Ave. North, Sherbrooke, QC J1H 5N4, Canada

Funder

Canadian Institutes of Health Research

National Institute on Drug Abuse

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.6b00097

Reference32 articles.

1. Neurotensin and pain modulation

2. Neurotensin and neurotensin receptors: Characteristic, structure–activity relationship and pain modulation—A review