Functional Interrogation of a Depression-Related Serotonergic Single Nucleotide Polymorphism, rs6295, Using a Humanized Mouse Model-Reference-Cited by-同舟云学术

Functional Interrogation of a Depression-Related Serotonergic Single Nucleotide Polymorphism, rs6295, Using a Humanized Mouse Model

Published:2019-01-29 Issue:7 Volume:10 Page:3197-3206
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Cunningham Ashley M.¹²,Santos Tabia L.¹,Gutzeit Vanessa A.¹,Hamilton Heather²,Hen René¹,Donaldson Zoe R.²^ORCID

Affiliation:

1. Division of Integrative Neuroscience, New York State Psychiatric Institute and Columbia University, New York, New York 10032, United States

2. Departments of Molecular, Cellular, and Developmental Biology and Psychology and Neuroscience, University of Colorado Boulder, Boulder, Colorado 80309, United States

Funder

U.S. Department of Health and Human Services

American Foundation for Suicide Prevention

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.8b00638

Reference52 articles.

1. Buspirone: Back to the Future

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3. Elevated anxiety and antidepressant-like responses in serotonin 5-HT1A receptor mutant mice

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5. Selective siRNA-mediated suppression of 5-HT1A autoreceptors evokes strong anti-depressant-like effects

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