Inhibition of 14-3-3/Tau by Hybrid Small-Molecule Peptides Operating via Two Different Binding Modes-Reference-Cited by-同舟云学术

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Inhibition of 14-3-3/Tau by Hybrid Small-Molecule Peptides Operating via Two Different Binding Modes

Published:2018-05-03 Issue:11 Volume:9 Page:2639-2654
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Andrei Sebastian A.¹^ORCID,Meijer Femke A.¹,Neves João Filipe²,Brunsveld Luc¹^ORCID,Landrieu Isabelle²,Ottmann Christian¹³^ORCID,Milroy Lech-Gustav¹^ORCID

Affiliation:

1. Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Technische Universiteit Eindhoven, Den Dolech 2, 5612 AZ Eindhoven, The Netherlands

2. UMR 8576 CNRS-Lille University, 59000 Villeneuve d’Ascq, France

3. Department of Chemistry, University of Duisburg-Essen, Universitätsstrasse 7, 45117 Essen, Germany

Funder

European Regional Development Fund

H2020 European Institute of Innovation and Technology

Centre National de la Recherche Scientifique

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

French State

CTRL CPER

French Ministry of Research

Laboratory of Excellence (LabEx)

European Community

University of Lille

Hauts de France Regional Council

M?tropole Europ?enne de Lille

Nord Region Council

Institut Pasteur de Lille

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

http://pubs.acs.org/doi/pdf/10.1021/acschemneuro.8b00118

Reference51 articles.

1. Alzheimer's disease drug development pipeline: 2017

2. Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

3. New Modalities for Challenging Targets in Drug Discovery

4. Small-molecule inhibitors of protein–protein interactions: progressing towards the dream

5. Reaching for high-hanging fruit in drug discovery at protein–protein interfaces

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1. Structure-Based Optimization of Covalent, Small-Molecule Stabilizers of the 14-3-3σ/ERα Protein–Protein Interaction from Nonselective Fragments;Journal of the American Chemical Society;2023-09-07

2. From Tethered to Freestanding Stabilizers of 14‐3‐3 Protein‐Protein Interactions through Fragment Linking;Angewandte Chemie International Edition;2023-08

3. From Tethered to Freestanding Stabilizers of 14‐3‐3 Protein‐Protein Interactions through Fragment Linking;Angewandte Chemie;2023-08

4. Insights into the Structural Conformations of the Tau Protein in Different Aggregation Status;Molecules;2023-06-04

5. Contemporary biophysical approaches for studying 14-3-3 protein-protein interactions;Frontiers in Molecular Biosciences;2022-11-08

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