Methylation Products of 6β-N-Heterocyclic Substituted Naltrexamine Derivatives as Potential Peripheral Opioid Receptor Modulators-Reference-Cited by-同舟云学术

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Methylation Products of 6β-N-Heterocyclic Substituted Naltrexamine Derivatives as Potential Peripheral Opioid Receptor Modulators

Published:2018-07-12 Issue:12 Volume:9 Page:3028-3037
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Zheng Yi¹,Obeng Samuel¹,Wang Huiqun¹,Stevens David L.²,Komla Essie²,Selley Dana E.²,Dewey William L.²,Akbarali Hamid I.²,Zhang Yan¹^ORCID

Affiliation:

1. Department of Medicinal Chemistry, Virginia Commonwealth University, 800 E. Leigh Street, Richmond, Virginia 23298, United States

2. Department of Pharmacology and Toxicology, Virginia Commonwealth University, 1112 East Clay Street, Richmond, Virginia 23298, United States

Funder

National Institute on Drug Abuse

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.8b00234

Reference66 articles.

1. Opioids and their receptors: Are we there yet?

2. Opioid receptors: Structural and mechanistic insights into pharmacology and signaling

3. The role of the opioid system in alcohol dependence

4. Management of opioid side effects in cancer-related and chronic noncancer pain: a systematic review

5. Opioid Receptors

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design, Synthesis, and Biological Evaluation of NAP Isosteres: A Switch from Peripheral to Central Nervous System Acting Mu-Opioid Receptor Antagonists;Journal of Medicinal Chemistry;2022-03-08

2. Verifying the role of 3-hydroxy of 17-cyclopropylmethyl-4,5α-epoxy-3,14β-dihydroxy-6β-[(4′-pyridyl) carboxamido]morphinan derivatives via their binding affinity and selectivity profiles on opioid receptors;Bioorganic Chemistry;2021-04

3. Endogenous Opiates and Behavior: 2018;Peptides;2020-10

4. Comparison of Pharmacological Properties between the Kappa Opioid Receptor Agonist Nalfurafine and 42B, Its 3-Dehydroxy Analogue: Disconnect between in Vitro Agonist Bias and in Vivo Pharmacological Effects;ACS Chemical Neuroscience;2020-09-08

5. Pharmacological characterization of 17-cyclopropylmethyl-3,14-dihydroxy-4,5-epoxy-6-[(3′-fluoro-4′-pyridyl)acetamido]morphinan (NFP) as a dual selective MOR/KOR ligand with potential applications in treating opioid use disorder;European Journal of Pharmacology;2019-12

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