Novel Bivalent 5-HT2A Receptor Antagonists Exhibit High Affinity and Potency in Vitro and Efficacy in Vivo-Reference-Cited by-同舟云学术

Novel Bivalent 5-HT2A Receptor Antagonists Exhibit High Affinity and Potency in Vitro and Efficacy in Vivo

Published:2017-11-07 Issue:3 Volume:9 Page:514-521
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Soto Claudia A.^ORCID,Shashack Matthew J.,Fox Robert G.,Bubar Marcy J.,Rice Kenner C.¹,Watson Cheryl S.,Cunningham Kathryn A.^ORCID,Gilbertson Scott R.²^ORCID,Anastasio Noelle C.^ORCID

Affiliation:

1. Drug Design and Synthesis Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse, Bethesda, Maryland 20892, United States

2. Department of Chemistry, University of Houston, Houston, Texas 77004, United States

Funder

National Institute on Alcohol Abuse and Alcoholism

National Institute on Drug Abuse

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.7b00309

Reference63 articles.

1. Molecular, pharmacological and functional diversity of 5-HT receptors