Design, Synthesis, and Biological Evaluation of 1-Benzylamino-2-hydroxyalkyl Derivatives as New Potential Disease-Modifying Multifunctional Anti-Alzheimer’s Agents

Author:

Panek Dawid1,Więckowska Anna1ORCID,Jończyk Jakub1,Godyń Justyna1,Bajda Marek1,Wichur Tomasz1,Pasieka Anna1,Knez Damijan2,Pišlar Anja2,Korabecny Jan34,Soukup Ondrej34,Sepsova Vendula34,Sabaté Raimon56ORCID,Kos Janko2,Gobec Stanislav2ORCID,Malawska Barbara1ORCID

Affiliation:

1. Department of Physicochemical Drug Analysis, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland

2. Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000 Ljubljana, Slovenia

3. Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic

4. Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defense, Trebesska 1575, 500 01 Hradec Kralove, Czech Republic

5. Department of Pharmacy and Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy and Food Science, University of Barcelona, Av Joan XXIII 27-31, 08028 Barcelona, Spain

6. Institute of Nanoscience and Nanotechnology (IN2UB), University of Barcelona, Av Joan XXIII, S/N, 08028 Barcelona, Spain

Funder

Javna Agencija za Raziskovalno Dejavnost RS

Narodowe Centrum Nauki

European Cooperation in Science and Technology

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

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