Defining Steric Requirements at CB1 and CB2 Cannabinoid Receptors Using Synthetic Cannabinoid Receptor Agonists 5F-AB-PINACA, 5F-ADB-PINACA, PX-1, PX-2, NNL-1, and Their Analogues

Author:

Markham Jack12,Sparkes Eric12,Boyd Rochelle12,Chen Shuli3,Manning Jamie J.3ORCID,Finlay David3ORCID,Lai Felcia4,McGregor Eila15,Maloney Callan J.12,Gerona Roy R.6,Connor Mark7ORCID,McGregor Iain S.15,Hibbs David E.4ORCID,Glass Michelle3ORCID,Kevin Richard C.14ORCID,Banister Samuel D.12ORCID

Affiliation:

1. The Lambert Initiative for Cannabinoid Therapeutics, Brain and Mind Centre, The University of Sydney, Sydney 2050, New South Wales, Australia

2. School of Chemistry, The University of Sydney, Sydney 2006, New South Wales, Australia

3. Department of Pharmacology and Toxicology, University of Otago, Dunedin 9016, New Zealand

4. School of Pharmacy, The University of Sydney, Sydney 2006, New South Wales, Australia

5. School of Psychology, The University of Sydney, Sydney 2005, New South Wales, Australia

6. Clinical Toxicology and Environmental Biomonitoring Laboratory, University of California, San Francisco, California 94143, United States

7. Faculty of Medicine and Health Sciences, Macquarie University, Sydney 2109, New South Wales, Australia

Funder

University of Sydney

National Health and Medical Research Council

Health Research Council of New Zealand

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

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