2-(4-Fluorophenyl)-1<i>H</i>-benzo[<i>d</i>]imidazole as a Promising Template for the Development of Metabolically Robust, α1β2γ2GABA-A Receptor-Positive Allosteric Modulators-Reference-Cited by-同舟云学术

2-(4-Fluorophenyl)-1H-benzo[d]imidazole as a Promising Template for the Development of Metabolically Robust, α1β2γ2GABA-A Receptor-Positive Allosteric Modulators

Published:2023-02-27 Issue:6 Volume:14 Page:1166-1180
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Marcinkowska Monika¹^ORCID,Fajkis-Zajączkowska Nikola¹,Szafrańska Katarzyna¹,Jończyk Jakub¹,Siwek Agata²,Mordyl Barbara²,Karcz Tadeusz³,Latacz Gniewomir³,Kolaczkowski Marcin¹^ORCID

Affiliation:

1. Department of Medicinal Chemistry, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Kraków, Poland

2. Department of Pharmacobiology, Faculty of Pharmacy Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Kraków, Poland

3. Department of Technology and Biotechnology of Drugs, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Street, 30-688 Kraków, Poland

Funder

Uniwersytet Jagiellonski Collegium Medicum

Narodowe Centrum Nauki

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.2c00800

Reference25 articles.

1. Can a Positive Allosteric Modulation of GABAergic Receptors Improve Motor Symptoms in Patients with Parkinson’s Disease? The Potential Role of Zolpidem in the Treatment of Parkinson’s Disease

2. A review of the evidence of zolpidem efficacy in neurological disability after brain damage due to stroke, trauma and hypoxia: A justification of further clinical trials

3. General Anesthesia, Sleep, and Coma

4. Replacement of histidine in position 105 in the α5subunit by cysteine stimulates zolpidem sensitivity of α5β2γ2GABAAreceptors

5. Increased Arousal in a Patient with Anoxic Brain Injury After Administration of Zolpidem

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