Acid-Induced Aggregation of Human Monoclonal IgG1 and IgG2: Molecular Mechanism and the Effect of Solution Composition-Reference-Cited by-同舟云学术

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Acid-Induced Aggregation of Human Monoclonal IgG1 and IgG2: Molecular Mechanism and the Effect of Solution Composition

Published:2010-10-11 Issue:43 Volume:49 Page:9328-9338
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Hari Sanjay B.¹²,Lau Hollis¹,Razinkov Vladimir I.¹,Chen Shuang¹³,Latypov Ramil F.¹

Affiliation:

1. Process and Product Development, Amgen Inc., Seattle, Washington 98119, United States

2. Department of Chemistry, University of Washington, Seattle, Washington 98195, United States

3. School of Chemical Engineering, Purdue University, West Lafayette, Indiana 47907, United States

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi100841u

Reference51 articles.

1. Protein aggregation and its inhibition in biopharmaceutics

2. Protein aggregation and bioprocessing

3. Principles, approaches, and challenges for predicting protein aggregation rates and shelf life

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